Anora employs the Single Nucleotide Polymorphism (SNP) Microarray method to discern these chromosomal irregularities. This encompasses the detection of abnormalities, including the absence or excess of chromosomal segments (Aneuploidy, Deletion, and Duplication), as well as the acquisition of an extra set of chromosomes, often inherited from either the mother or the father (Uniparental Disomy; UPD), all of which can be identified from the POC sample. Furthermore, the examination extends its capability to explore the origin of the genetic anomaly that led to the miscarriage, distinguishing whether it emanated from the father or mother. This comprehensive analysis incorporates samples from both parents, reducing the potential for errors stemming from maternal sample contamination during the collection process, a phenomenon known as Maternal Cell Contamination (MCC).
• Expectant mothers who have a prior history of giving birth to a child with abnormal chromosomes.
• Expectant mothers seeking insights into the factors contributing to miscarriage.
• Expectant mothers who have experienced multiple miscarriages.
• Expectant mothers interested in assessing their likelihood of a recurring miscarriage.
• Irregularities in any pair of somatic chromosomes, including T21 (resulting in Down syndrome), T18 (leading to Edwards syndrome), or T13 (associated with Patau syndrome).
• The presence of an extra chromosome in every chromosomal pair, known as Triploidy syndrome.
• Microdeletion syndromes such as DeGeorge syndrome, Prader-Willi syndrome, Angelman syndrome, Cri-du-chat syndrome, and more.
• Acquiring a full set of chromosomes, typically inherited from only one parent, referred to as Uniparental Disomy (UPD).
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