BRCA Testing for Hereditary Breast & Ovarian Cancers serves as a screening method for hereditary breast and ovarian cancer syndrome (HBOC) arising from genetic abnormalities. This genetic material is inherited from one generation to the next, predominantly associated with mutations in the BRCA1 and BRCA2 genes, along with various other genes. The statistical representation of the mutation risk in the BRCA1 and BRCA2 genes for the population is presented in the table below.
The impact of BRCA1 and BRCA2 gene mutations on populations
• A personal history of breast or ovarian cancer diagnosed at young age (premenopausal), bilateral breast cancer (affecting both breasts) or the presence of both ovarian and breast cancer
• A family history of breast, ovarian, fallopian tube, peritoneal, prostate, or pancreatic cancer
• A male family member having breast cancer
• A relative with a known deleterious mutation in BRCA1 or BRCA2 genes
• A history of breast cancer diagnosed below age of 45 years
• A family member with bilateral breast cancer below age of 50
• An individual with triple negative breast cancer below age of 60 years with or without family history
• Two or more relatives with ovarian cancer
• Both breast and ovarian cancers in either the same woman or the same family
• Enables the comprehensive examination of multiple mutation sites, encompassing both the BRCA1 and BRCA2 genes. It proficiently identifies Single Nucleotide Variations (SNVs), short insertions and deletions (InDels), structural variants, and copy number variations in a single test
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อีเมล : info@bccgroup-thailand.com